Address

(Office): Rm G88, Science Centre South Block

(Lab): Rm G90, Science Centre South Block

 People SSM
 

Phone

(Office): (852) 3943 5593

(Lab): (852) 3943 6286
Fax (852) 2603 6382
Email This email address is being protected from spambots. You need JavaScript enabled to view it.
Web -

 

Education

1973 Ph.D. University of Wisconsin-Madison
1970 M.Phil. University of Hong Kong
1968 B.Sc. Sp. Hon., University of Hong Kong
1966 B.Sc. Cum laude, Chinese University of Hong Kong

Position

  • Research Professor of Biology, School of Life Sciences
  • Professor Emeritus, School of Biological Sciences
  • Director, State Key Laboratory of Agrobiotechnology (CUHK)
  • Director, Institute of Plant Molecular Biology and Agricultural Biotechnology
  • Master, S.H. Ho College

Research Interests

 

  • Plant Molecular biology: plant gene structure, expression and regulation
  • Plant and agriculural biotechnology: crop improvement on rice yield and nutritional quality and development of an efficient plant seed bioreactor including downstream purification of recombinant proteins

Representative Publications

  • Lam HM, Xu X, Liu X, Chen W, Yang GH, Wong FL, Li MW, He WM, Qin N, Wang B, Li J, Jian M, Wang J, Shao GH, Wang J, Sun SSM, Zhang GY:2010. Resequencing of 31 wild and cultivated soybean genomes identifies patterns of genetic diversity and selection. Nat Genet 2010,42:1053-1059.
  • Lau OS, Ng WK, Liu WL, Chang SP, Sun, SSM: Production of the 42-kDa fragment of Plasmodium falciparum merozoite surface protein 1, a leading malaria vaccine antigen, in Arabidopsis thaliana seeds. Plant Biotech J 2010, 8:994-1004
  • Lau OS, Sun, SSM: Plant seeds as bioreactors for recombinant protein production. Biotech Advances (Invited Review) 2009, 27:1015-1022.
  • Sun SSM: Application of agricultural biotechnology to improve food nutrition and healthcare products (Review Article). Asia Pac J Clin Nutr 2008,17(S): 87-90.
  • Yuan DY, Duan MJ, Tan YN, Yi ZL, Yuan LP, Sun SSM: Generating marker-free transgenic homozygous rice restorer lines with PEPC and PPDK genes by Agrobacterium-mediated transformation using super binary vector. Hybrid Rice 2007, 22:57-63.
  • Xiao GY, Yuan LP, Sun SSM: Strategy and utilization of herbicide resistance gene in two-line hybrid rice. Mol Breeding 2007, 20:287-292.
  • Duan MJ, Sun SSM: Profiling the expression of genes controlling rice grain quality Plant. Plant Mol Biol 2005, 59:165-178.
  • Altenbach SB, Pearson KW, Meeker G, Staracy L, Sun SSM: Enhancement of the methionine content of seed protein by the expression of a chimeric gene encoding a methionine-rich protein in transgenic plants. Plant Mol Biol 1989, 13:513-522.
  • Sun SSM: Methionine enhancement in plants.In: Plant Amino Acids: Biochemistry and Biotechnology, Singh BK ed, Marcel Dekker Inc, N.Y. 1999, pp. 509-522.
  • Sun SSM, Slightom JS, Hall TC: Intervening sequence in a plant gene: comparison of the partial sequence of cDNA and genomic DNA of French bean phaseolin. Nature 1981, 289:37-41.

Research Grants

  • 2007-2011, UGC-AoE, Plant and Agricultural Biotechnology Centre, Sun SSM, PI/Director, HK $25,000,000
  • 2009-2011, 國家重大轉基因專項 (National Transgenic Project), 作物產量、抗逆和高營養相關功能基因的發掘與機理研究 (Identification and mechanistic study of genes related to crop yield, nutrition and stress tolerance), 人民幣 295萬(RMB 2.95M)
  • 2000-2006, UGC-AoE, Plant and Fungal Biotechnology, Sun SSM, PI/Director, HK $38,800,000
  • 2006-2011, Bill & Melinda Gates Foundation, Improving rice for high beta-carotene, vitamin E, quality protein and iron and zinc bio-availability, Sun SSM, Consortium member, US $1.0M
  • 2005-2008, GRF, The biology of vacuolar sorting receptor proteins and their applications in plant, HK $1,446,675
  • 1998-2001. GRF, Engineering in Brazil nut Met-rich protein for reduced allergenic activity, HK$1,211,000
  • 1998-2001, ITF, Production of high value pharmaceutical proteins in transgenic seeds, HK $5,292,000
  • 1999-2002, RGC Central Allocation, Automated Microbial Identification system, HK $2,980,000,
  • 1997-1999, GRF, Genetic engineering of sweet protein mabinlin for increased stability, HK $656,640
  • 1996-1998, GRF, Genetic engineering of rapeseed for enhanced nutritional quality, HK $722,000

Patents

Granted:

  • Sun SSM and Chen DM: Epitope identification and modification for reduced allergic activity in proteins targeted for transgenic expression (US patent # 7,399,597; Appl # 11/099,856), 2008
  • Sun SSM and Liu QQ: Method to produce desired proteins in plants.” (US patent # 7,425,667), 2008
  • Sun SSM, Lam HM and Fung MC: Transgenic plant product comprising human granulocyte colony-stimulating factor and method for preparing the same (HK patent # 1071908), 2007
  • Sun SSM, Lam H.M and Fung MC: Transgenic plant product comprising human granulocyte colony-stimulating factor and method for preparing the same (Chinese patent # 200410037474.X), 2007

Pending:

  • Sun SSM and Tian L: A cost-effective method for expression and purification of recombinant proteins in plants (US patent # 61/425,703), filed 2010
  • Sun SSM and Liu QQ: Method to produce desired proteins in plants (HK patent # 09102272.6), filed 2009
  • Sun SSM and Liu QQ: Method to produce desired proteins in plants (Chinese patent # 200680041156.8), filed 2006
  • Sun SSM, Lam HM and Fung MC: Transgenic plant product comprising human granulocyte colony-stimulating factor and method for preparing the same (US patent# 10/611,226), filed 2003

 Awards

 

  • Member, the Chinese Academy of Engineering, 2003
  • Member, the International Eurasian Academy of Sciences, 2008
  • Leader of the Year 2005 (Education/Research), Hong Kong, 2005
  • Distinguished Alumnus Award of Science Faculty at the University of Hong Kong, 2009
  • Honorary Fellow of the Chinese University of Hong Kong, 2010.
  • Friendship Medal: Awarded by the State Government of China to experts making outstanding contributions to the modernization of China, 1996
  • Greatwall Friendship Award: Awarded by the People’s Government of Beijing Municipality, for contribution to Beijing’s construction and friendly cooperation in science and technology, 2000
  • Science and Technology Award, 2nd Class, by the People’s Government, Zhejiang Province, China, for development and application of a high efficient, safe, and large scale rice transformation platform, 2007.
  • ARCO Distinguished Research Award, 1984

 

Professional Activities

  • Member, University Grants Council, Hong Kong SAR, 2007-2010
  • Member, Academic Council on Biotechnology, National Laboratory of Agrobiotechnology, China Agricultural University, China, 1990-present
  • Member, Academic Committee, National Key Lab on Rice Biology, China Rice Research Institute and Zhejiang University, China, 2005 - 2010
  • Member, Advisory Committee, Institute of Plant and Microbial Biology, Academia Sinica, Taiwan, 2001-2007
  • Professor/Honorary/Adjunct/Visiting Professor at: Tsinghua University, 2004-present, China Agricultural University, 1989-present; Nankai University, 1999-present; University of Science and Technology of China, 1999-present; Wuhan University, 1999-present; Huazhong Agricultural University, 2002-present; Zhejiang University, 2003-present; Yangzhou University, 2004-presen; Northwestern Agricultural University, 1997-present; Tianjin University of Science and Technology, 2009-present; Ocean University of Zhanjiang, China, 2001-present
  • Board of Editors, Acta Agronomica Sinica, China, 2002-present
  • Editorial Board, Tropical Plant Biology, 2007-present
  • Editorial Board, Science and Technology in China, 2004-2007
  • Biology and Medicine Panel, Research Grants Council, Hong Kong, 1996-2001
  • Member, Innovation and Technology Fund (Biotechnology Projects) Vetting Committee, Hong Kong, 2000
  • Convenor, Coordination Committee of the 3rd (2001) and 6th (2007), and member of Organization Committee (since 1999), Cross-Strait Symposium on Plant Molecular Biology and Biotechnology, China, Taiwan and Hong Kong

 

 

 

 

 

 

Address

(Office): Rm 603A, Mong Man Wai Building, CUHK
(Lab): Rm 619, Mong Man Wai Building, CUHK

   People Jerome Hui
 

Phone

(Office): (852) 3943 6316
(Lab): (852) 3943 6115

  
Fax (852) 2603 7246  
Email This email address is being protected from spambots. You need JavaScript enabled to view it.
  
Web

http://sites.google.com/site/huijerome/

http://biodiversity.sls.cuhk.edu.hk/ebphk/

  
     

Education

2008 DPhil, University of Oxford
2005 MPhil, The University of Hong Kong
2003 BSc, The University of Hong Kong


Position

  • Professor, School of Life Sciences
  • Director, Biology Programme (BIOL)
  • Double Major in Biology and Chemistry Programme (DMBC)
  • Director, MSc in Biodiversity, Environmental Management, Sustainability and Technology (BEST)
  • Simon F.S. Li Marine Science Laboratory (MSL)
  • State Key Laboratory of Agrobiotechnology (SKLA)
  • Institute of Environment, Energy and Sustainability (IEES)
  • Institute of Future Cities (IOFC)
  • New Asia College (NAC)

 
Research Interests

  • Arthropod and insect biology, Cnidarians, Invertebrates, Animal-plant interactions
  • Sesquiterpenoid hormones, microRNAs
  • Marine biotechnology, Molecular ecology and conservation of biodiversity
  • Evolutionary biology, Genomics


Representative Publications

Full Publication List
^ = contributed equally ; * = corresponding author

  • Li C^, Chan KK^, Nong WY^, Chen SS^, So WL, Qu Z, Wu HY, Yip HY, Chan CB, Tobe SS, Bendena WG, Kai ZP*, Hui JHL*. (2024). Insect metamorphosis is regulated differently between sexes by members of a microRNA cluster. eLife. 
  • Law ST^, Yu Y^, Nong WN^, So WL, Li Y, Swale T, Ferrier DE*, Qiu JW*, Qian PY*, Hui JHL*. (2023). The genome of the deep-sea anemone Actinernus sp. contains a mega-array of ANTP-class homeobox genes. Proceedings of the Royal Society B, 290, 20231563.
  • Lee IH^, Nong WY^, So WL^, Cheung CK, Xie Y, Baril T, Yip HY, Swale T, Chan SK, Wei YY, Lo N, Hayward A, Chan TF, Lam HM, Hui JHL*. (2023). Sex-dependent responses to temperature in the common yellow butterfly Eurema hecabe. BMC Biology, 21, 200.
  • So WL^, Nong WY^, Xie Y^, Baril T^, Yao MH, Qu Z, Haimovitz J, Swale T, Gaitan-Espitia JD, Lau KF, Tobe SS, Bendena WG, Kai ZP, Hayward A*, Hui JHL*. (2022). Myriapod genomes reveal ancestral horizontal gene transfer and hormonal gene loss in millipedes. Nature Communications, 13, 3010.
  • Nong WY^, Yu Y^, Aase-Remedios M^, Xie Y, So WL, Li Y, Wong CF, Baril T, Law ST, Lai SY, Haimovitz J, Swale T, Chen SS, Kai ZP, Sun X, Wu Z, Hayward A, Ferrier DE*, Hui JHL*. (2022). Genome of the ramshorn snail Biomphalaria staminea - an obligate intermediate host of schistosomiasis. GigaScience, giac012.
  • Nong WY^, Qu Z^, Li YQ^, Barton-Owen T^, Wong AY^, Yip HY, Lee HT, Narayana S, Baril T, Swale T, Cao J, Chan TF, Kwan HS, Ngai SM, Panagiotou G, Qian PY, Qiu JW, Yip KY, Ismail N, Pati S, John A, Tobe SS, Bendena WG, Cheung SG, Hayward A, Hui JHL*. (2021). Horseshoe crab genomes reveal the evolutionary fates of genes and microRNAs after three rounds (3R) of whole genome duplication. Communications Biology, 4, 83.
  • Qu Z^, Yiu WC^, Yip HY^, Nong WY^, Yu CW, Lee IH, Wong AY, Wong NW, Cheung FK, Chan TF, Lau KF, Zhong S, Chu KH, Tobe SS, Ferrier DE, Bendena WG, Hui JHL*. (2020). MicroRNA clusters integrate evolutionary constraints on expression and target affinities: the miR-6/5/4/286/3/309 cluster in Drosophila. Molecular Biology and Evolution, 37(10), 2955-2965.
  • Qu Z^, Nong WY^, So WL^, Barton-Owen T^, Li YQ^, Leung TC, Li C, Baril T, Wong AY, Swale T, Chan TF, Hayward A, Ngai SM, Hui JHL*. (2020). Millipede genomes reveal unique adaptation of genes and microRNAs during myriapod evolution. PLOS Biology, 18(9), e3000636.
  • Nong WY^, Cao JQ^, Li YQ^, Qu Z^, Leung TC, Sun J, Swale T, Yip HY, Qian PY, Qiu JW, Kwan HS, Bendena WG, Tobe SS, Chan TF, Yip KY, Chu KH, Ngai SM, Tsim KY, Holland PW*, Hui JHL*. (2020). Jellyfish genomes reveal distinct homeobox gene clusters and conservation of small RNA processing. Nature Communications, 11, 3051.
  • Nong WY^, Law ST^, Wong AY, Baril T, Swale T, Chu LM, Hayward A, Lau DT, Hui JHL*. (2020). Chromosomal-level reference genome of the incense tree Aquilaria sinensis. Molecular Ecology Resources, 20(4), 971-979.
  • Hui JHL* (2018). Copepod incompatibilities. Nature Ecology and Evolution. 2(8). 1203-1204.
  • Qu Z, Bendena WG, Nong WY, Siggins KW, Noriega F, Kai ZP, Zang YY, Koon AC, Chan HY, Chan TF, Chu KH, Lam HM, Akam M, Tobe SS, Hui JHL* (2017). MicroRNAs regulate the sesquiterpenoid hormonal pathway in Drosophila and other arthropods. Proceedings of the Royal Society of London B, 284, 1869.
  • Kenny NJ, Sin YW, Hayward A, Paps J, Chu KH, Hui JHL*. (2015). The phylogenetic utility and functional constraint of microRNA flanking sequences. Proceedings of the Royal Society of London B, 282(1803), 2014983.

Research Grants

  • 2025-2028, RGC RIF, EarthBioGenome Project Hong Kong: Butterflies and Next generation of scientists, $7,900,000
  • 2024-2027, RGC GRF, Sesquiterpenoids in chelicerates: Farnesoic acid and methyl farnesoate as functional hormones?, $1,553,391
  • 2023-2026, RGC GRF, Decoding the myriapod genomes and microRNAs to understand how evolutionary novelties arise in arthropods, $1,593,380
  • 2022-2025, NSFC/RGC, Population genomics of a freshwater snail and risk assessment of imported schistosomiasis transmission, $1,185,561
  • 2022-2023, CORE, Investigation of small RNA roles in a laboratory coral model under climate change, $400,000
  • 2021-2024, RGC CRF, EarthBioGenome Project: Hong Kong, $3,250,000
  • 2021-2022, HKB, Decoding the genome of a deep sea animal, $700,000
  • 2021-2023, RGC GRF, Sesquiterpenoids in insects: MicroRNA cluster co-operation? $1,081,443
  • 2020-2021, SADF, Agricultural pests commonly found in Hong Kong, $2,512,026
  • 2019-2022, RGC GRF, Sesquiterpenoids in non-insect arthropods: Farnesoic acid and methyl farnesoate as major hormones in millipedes? $1,099,558
  • 2019-2020, ECF, Working out the soil biodiversity of millipedes in Hong Kong, $1,121,500
  • 2019-2020, RGC PROCORE, Tissue regeneration in invertebrate animals under climate change, $45,000
  • 2018-2019, ECF, Development of environmental DNA (eDNA) protocol for horseshoe crabs, $499,680
  • 2016-2019, RGC GRF, MicroRNA flanking sequence: a novel target for studying microRNA arm switching?, $651,203
  • 2015-2016, HMRF, Distribution and current infection status of African schistosomiasis transmitting snails in Hong Kong, $99,799
  • 2015-2018, RGC ECS, Regulation of the biosynthesis of sesquiterpenoid hormones by microRNAs in arthropods, $600,000

Research Contracts

  • 2018-2021, AFCD, Investigate population structure and identify genetic markers for conservation of incense tree, $2,799,991
  • 2018-2020, AFCD, Juvenile horseshoe crab monitoring using field surveys and environmental DNA technique in Hong Kong, $2,799,997
  • 2018-2019, AFCD, Molecular analysis of animal samples, $50,000
  • 2017-2021, FEHD, Zika virus surveillance and study on native Wolbachia infection in mosquitoes, $1,405,103
  • 2016-2017, AFCD, Genetic study of seagrass in Hong Kong, $49,910


Teaching Grants

  • 2024, RDMDF, Biodiversity genomic, transcriptomic and Sanger sequencing data management: Common practices and workshops, $99,000
  • 2021-2022, CDG, Basic laboratory techniques in studying biology: species identification, dissection, field collection, molecular biology, and genetics, $99,050
  • 2017-2018, CDG, Animated courseware in evolutionary biology, $95,000


Awards

  • 2021, The Faculty Young Researcher Award, CUHK
  • 2014, 2018, The Faculty Exemplary Teaching Award, CUHK

Others

  • Advisory Council on Food and Environmental Hygiene (Working Group)
  • Environmental Campaign Committee
  • Fellow of The Royal Society of Biology (FRSB)
  • Editorial board - Frontiers in Ecology and Evolution, Frontiers in Endocrinology, Frontiers in Genetics, Frontiers in Physiology, Frontiers in Plant Science, Journal of the Marine Biological Association of the United Kingdom, Scientific Data
  • International Biology Olympiad Hong Kong Contest Steering Committee
  • HKDSE Biology Subject Committee
  • Genetic Modified Organisms (Control of Release) Ordinance Expert Group
  • Fung Yuen Butterfly Reserve Advisory Committee
  • IUCN SSC horseshoe crab specialist group
  • The International Barcode of Life (iBOL) Consortium
  • Hong Kong Biodiversity Genomics Consortium
  • RGC S-Panel of HKPFS and JRFS

 

Address

(Office): Rm 604, Mong Man Wai Building, CUHK
(Lab): Rm 612A, Mong Man Wai Building, CUHK

 People HMC 

Phone

(Office): (852) 3943 1530
(Lab): (852) 3943 0577
Fax (852) 2603 7732
Email This email address is being protected from spambots. You need JavaScript enabled to view it.
Web https://orcid.org/0000-0003-1203-2096
 

 


Education

2011    
PhD (Pharmacology and Pharmacy, Medicine), University of Hong Kong
2007
MPhil (Physiology), University of Hong Kong
2005 BSc (Animal and Plant Biotechnology), University of Hong Kong

Positions

2019+          Assistant Professor, School of Life Sciences, CUHK
2015-2019   Junior Fellow, Institute for Advanced Study, HKUST
2015-2019   Research Assistant Professor, Division of Life Science, HKUST
2013-2015   Postdoctoral Fellow, Division of Life Science, HKUST
2010-2011   Postdoctoral Fellow, School of Electrical and Computer Engineering, Cornell University, USA

Research Interests

  1. Metabolic changes in Alzheimer’s disease and related dementia
  2. Neuronal senescence and brain aging

 Representative Publications

 (For the full list of records, please refer to the ORCID)

  1. Wandi Xiong, Kaiyu Xu, Jacquelyne Ka-Li Sun, Siling Liu, Baizhen Zhao, Jie Shi, Karl Herrup, Hei-Man Chow, Lin Lu, Jiali Li. (2024) mtDNA-derived lncMtDloop regulates mitochondrial homeostasis and implications in AD. EMBO Journal. 2024 Oct 18;43(23):6001–6031. doi: 10.1038/s44318-024-00270-7. [Co-corresponding author, Clarivate Ranking: 23/313 Biochemistry & Molecular Biology (Q1), Clarivate impact factor2023: 9.4]
  2. Deng Wu, Jacquelyne Ka Li Sun, Kim Hei-Man Chow. (2024) Neuronal cell cycle re-entry events in the aging brain are more prevalent in neurodegeneration and lead to cellular senescence. PLOS Biology. 2024 Apr 23;22(4):e3002559. doi: 10.1371/journal.pbio.3002559 [Corresponding author, Clarivate Ranking: 5/109 Biology (Q1), Clarivate impact factor2023: 7.8]
  3. Dina Popova, Jacquelyne Ka Li Sun, Hei-Man Chow, Ronald P Hart. (2024) A critical review of ethanol effects on neuronal firing: A metabolic perspective. Alcohol: Clinical and Experimental Research. 2024 Jan 12. doi: 10.1111/acer.15266. [Co-corresponding author, Clarivate Ranking: 17/55 in Substance Abuse (Q2), Clarivate impact factor2023: 3.0]
  4. Deng Wu, Xiaoman Bi, Kim Hei-Man Chow. (2024) Identification of female-enriched and disease-associated microglia (FDAMic) contributes to sexual dimorphism in late-onset Alzheimer’s disease. Journal of Neuroinflammation. 2024 Jan 4;21(1):1. doi: 10.1186/s12974-023-02987-4. [Corresponding author, Clarivate Ranking: 13/181 in Immunology (Q1), Clarivate impact factor2023: 9.3]
  5. Jacquelyne Ka-Li Sun, Genper Chi-Ngai Wong and Kim Hei-Man Chow. (2023) Crosstalk between DNA damage response and the central carbon metabolic network underlies selective vulnerability of Purkinje neurons in Ataxia-telangiectasia. Journal of Neurochemistry 2023 Aug;166(4):654-677. doi: 10.1111/jnc.15881. [Corresponding author, Clarivate Ranking: 78/310 in Neurosciences (Q1), Clarivate impact factor2023: 4.2]
  6. Deng Wu, Xiaoman Bi, Peihu Li, Dahua Xu, Jianmin Qiu, Kongning Li, Shaojiang Zheng, Kim Hei-Man Chow. (2023) Enhanced insulin-regulated phagocytic activities support extreme health span and longevity in multiple populations. Aging Cell 2023 Mar 8;e13810. [Lead co-corresponding author, Clarivate Ranking: 5/74 in Geriatrics & Gerontology (Q1), Clarivate impact factor2023: 8.0]
  7. Jacquelyne Ka-Li Sun, Deng Wu, Genper Chi-Ngai Wong, Tsun-Ming Lau, Meigui Yang, Ronald P Hart, Kin-Ming Kwan, Ho-Yin Edwin Chan, Hei-Man Chow. (2023) Chronic alcohol metabolism results in DNA repair infidelity and cell-cycle-induced senescence in neurons. Aging Cell 2023 Feb; 22(2):e13772. [Corresponding author, Clarivate Ranking: 5/74 in Geriatrics & Gerontology (Q1), Clarivate impact factor2023: 8.0]
  8. Genper Chi-Ngai Wong and Kim Hei-Man Chow (2022) DNA damage response-associated cell cycle re-entry and neuronal senescence in brain aging and Alzheimer’s disease. Journal of Alzheimer’s Disease 2022 Jul 11. doi: 10.3233/JAD-220203 [Corresponding author, Clarivate Ranking: 116/310 in Neurosciences (Q1), Clarivate impact factor2023: 3.4]
  9. Hei-Man Chow, Jacquelyne Ka-Li Sun, Ronald P Hart, Kenneth King-Yip Cheng, Clara HL Hung, Tsun-Ming Lau, Kin-Ming Kwan. (2021) Low-density lipoprotein receptor-related protein 6 cell surface availability regulates fuel metabolism in astrocytes. Advanced Science. 2021 Aug;8(16):e2004993. doi: 10.1002/advs.202004993 [Corresponding author, Clarivate Ranking: 18/230 in Chemistry, Multidisciplinary (Q1), Clarivate impact factor2022: 14.3]
  10. Jiechao Zhou, Hei-Man Chow, Yan Liu, Di Wu, Meng Shi, Jieyin Li, Lei Wen, Yuehong Gao, Guimiao Chen, Kai Zhuang, Hui Lin, Guanyun Zhang, Wenting Xie, Huifang Li, Lige Leng, Mengdan Wang, Naizhen Zheng, Hao Sun, Yingjun Zhao, Yunwu Zhang, Maoqiang Xue, Timothy Y Huang, Guojun Bu, Huaxi Xu, Zengqiang Yuan, Karl Herrup, Jie Zhang. (2020) Cyclin-Dependent Kinase 5-Dependent BAG3 Degradation Modulates Synaptic Protein Turnover. Biological Psychiatry 2020 Apr 15;87(8):756-769. doi: 10.1016/j.biopsych.2019.11.013. [Co-corresponding author, Clarivate Ranking: 6/276 in Psychiatry (Q1), Clarivate impact factor2023: 9.6]
  11. Hei-Man Chow, Meng Shi, Aifang Cheng, Yuehong Gao, Guimiao Chen, Xuan Song, Raphaella Wai Lam So, Jie Zhang, Karl Herrup. (2019) Age-related hyperinsulinemia leads to insulin resistance in neurons and cell-cycle-induced senescence. Nature Neuroscience. 2019 Nov;22(11):1806-1819. doi: 10.1038/s41593-019-0505-1. [Co-corresponding author, Clarivate Ranking: 4/310 in Neurosciences (Q1), Clarivate impact factor2023: 21.2]
  12. Hei-Man Chow, Aifang Cheng, Xuan Song, Mavis R Swerdel, Ronald P Hart, Karl Herrup. (2019) ATM is activated by ATP depletion and modulates mitochondrial function through NRF1. Journal of Cell Biology. 2019 Mar 4;218(3):909-928. doi: 10.1083/jcb.201806197. [Co-corresponding author, Clarivate Ranking: 38/205 in Cell Biology (Q1), Clarivate Impact factor2023: 7.4]
  13. Karl Herrup, Kai-Hei Tse and Hei-Man Chow. (2017) Loopholes in the DNA contract kill neurons. Nature Neuroscience. 2017 Aug 29;20(9):1192-1194. doi: 10.1038/nn.4626 [Co-corresponding author, Clarivate Ranking: 4/310 in Neurosciences (Q1), Clarivate impact factor2023: 21.2]
  14. Hei-Man Chow, Karl Herrup. (2015) Genomic integrity and the ageing brain. Nature Reviews Neuroscience. 2015 Nov;16(11):672-84. doi: 10.1038/nrn4020 [1st author, Clarivate Ranking: 2/310 in Neurosciences (Q1), Clarivate impact factor2023: 28.7]
  15. Hei-Man Chow, Dong Guo, Jie-Chao Zhou, Guan-Yun Zhang, Hui-Fang Li, Karl Herrup, Jie Zhang. (2014) CDK5 activator protein p25 preferentially binds and activates GSK3β. PNAS. 2014 Nov 11;111(45):E4887-95. doi: 10.1073/pnas.1402627111. [1st author; Clarivate Ranking: 13/134 in Multidisciplinary Science (Q1), Clarivate impact factor2023: 9.4]
  16. Kim Hei-Man Chow, Raymond Wai-Yin Sun, Janice B B Lam, Carrie Ka-Lei Li, Aimin Xu, Dik-Lung Ma, Ruben Abagyan, Yu Wang, Chi-Ming Che. (2010) A gold(III) porphyrin complex with antitumor properties targets the Wnt/beta-catenin pathway. Cancer Research. 2010 Jan 1;70(1):329-37. doi: 10.1158/0008-5472.CAN-09-3324. [1st author, Clarivate Ranking: 30/322 in Oncology (Q1), Clarivate impact factor2023: 12.5]
  17. Janice B B Lam, Kim Hei-Man Chow, Aimin Xu, Karen S L Lam, Jing Liu, Nai-Sum Wong, Randall T Moon, Peter R Shepherd, Garth J S Cooper, Yu Wang. (2009) Adiponectin Haploinsufficiency Promotes Mammary Tumor Development in MMTV-PyVT Mice by Modulation of Phosphatase and Tensin Homolog Activities. PLoS ONE 2009;4(3):e4968. doi: 10.1371/journal.pone.0004968 [Co-1st author, Clarivate Ranking: 31/134 in Multidisciplinary Sciences (Q1), Clarivate impact factor2023: 2.9]

Research Grants

 [As Principal Investigator (PI) /Co-PI/ Project Coordinator (PC)]

 I. Extramural competitive grants

  1. PI, General Research Fund 2024/25. PKM2 moonlighting as the bimodal switch for aerobic glycolysis and cell cycle gene re-expression in neurons after sustained insulin exposure—Implications in Alzheimer’s disease (AD). Research Grants Council, HK$ 1,559,580, 01/01/2025-31/12/2027.
  2. PI, Young Scientist Fund 2023. ATM as a critical mediator of insulin-regulated metabolic flexibility and the related implications in cerebellar ataxia. National Natural Science Foundation of China, CYN$ 300,000, 01/01/2024-31/12/2026.
  3. Co-PI, Young Collaborative Research Fund 2021/22. Light Protects Vision: Optogenetic Activation of Trk Signaling for Neuroprotection of Retinal Ganglion Cells in Ocular Diseases. Research Grants Council, HK$ 3,755,333, 30/06/2023-29/06/2026. (Project Coordinator: Prof. Liting Duan, CUHK; with HK$ 400,000 allocated).
  4. Co-PI, Collaborative Research Fund 2021/22. Establishment of Spatial Multi-Omics Core Facility. Research Grants Council, HK$ 2,000,000. 30/06/2023-29/06/2026. (Project Coordinator: Prof. Andrew Man-Lok Chan, CUHK).
  5. Co-PI, Collaborative Research Fund 2020/21. The First Integrated State-of-the-Art Live Cell Imaging Platforms to Timely Promote Interdisciplinary and Advanced Life Sciences Research in Hong Kong and Beyond. Research Grants Council, HK$ 10,000,000. 30/06/2022-29/06/2025. (Project Coordinator: Prof. Liwen Jiang, CUHK).
  6. PI, Early Career Scheme 2021/22, Chronic alcohol consumption induces brain metabolic reprogramming: implications in accelerated brain aging and potentials of senolytics-based therapies. Research Grants Council, HK$ 1,185,691, 01/01/2022-31/12/2024.
  7. PI, Excellent Young Scientists Fund 2020, Metabolic reprogramming mechanism and regulation in cerebellar ataxia. National Natural Science Foundation of China, CYN$ 1,200,000, 01/01/2021-31/12/2023.
  8. Co-PI, Collaborative Research Fund 2019/20, The First Integrated State-of-the-Art Sample Preparation System for Cryo-Electron Microscopy/Tomography Analysis to Promote Advanced Cellular and Structural Biology Research in Hong Kong. Research Grants Council, HK$ 7,439,308, 30/06/2020-29/06/2023. (Project Coordinator: Prof. Liwen Jiang, CUHK).
  9. PI, General Research Fund 2019/20, Loss of nuclear estrogen-related receptor-a (ERRa) activity impairs metabolic plasticity and mitochondrial OXPHOS in neurons: Implications of sex differences observed in Alzheimer’s disease. Research Grants Council, HK$ 911,408, 01/01/2020-31/12/2022.
  10. PI, General Research Fund 2018/19, A novel ATM-NRF1 axis facilitates mito-nuclear communication in response to cellular energy demand—Implications for cerebellar neurodegeneration in Ataxia-telangiectasia. Research Grants Council, HK$ 972,000, 01/07/2018-31/12/2021.
  11. PI, General Research Fund 2017/18, The Wnt antagonist Dkk1 acts as a bimodal switch of Wnt signaling that controls the neurotrophic versus neurotoxic fates of astrocytes: Implications in the Alzheimer’s disease. Research Grants Council, HK$ 819,393, 01/01/2018-31/12/2019.
  12. PI, Alzheimer’s Association Research Fellowship 2017. Targeting brain insulin resistance-mediated neuronal dysfunction in AD. Alzheimer’s Association, US$ 175,000, 01/10/2017-31/09/2021.

 II. Intramural competitive grants

  1. PC, Strategic Seed Funding for Collaborative Research Scheme. A pilot multi-omics investigation at whole tissue, sub-lobular, and cellular levels to profile the spatial and temporal changes in maturing cerebellum of the Fragile X syndrome—implications in autism. CUHK-Research Committee. HK$500,000, 1/11/2023-31/10/2025.
  2. PC, Seed Fund from School of Life Sciences for future CRF application 2022-23. Dissecting the role of FMR1 in regulating thyroid hormonal signaling and mitochondrial functions in the maturing cerebellum. CUHK-Research Committee. HK$ 200,000, 01/06/2023-31/05/2024.
  3. PC, CUHK-Academic Equipment Grant 2021/22. The Integrated Neuroscience and Metabolic Phenotypic Core (INMPC). HK$3,433,742, 06/03/2022-21/08/2022.
  4. PI, Direct Grants 2019/20. Metabolic Rewiring and Bioenergetic Adaption in Cerebellar Ataxia. CUHK-Research Committee, HK$ 150,000, 01/03/2020-31/08/2021.

Research Awards

  1. Faculty Young Researcher Award, Faculty of Science, The Chinese University of Hong Kong, Hong Kong, 02/2025.
  2. International Health Policy Fellowship, The National Academy of Medicine (NAM), USA, 07/2023-12/2025.
  3. Faculty Exemplary Teaching Award, Faculty of Science, CUHK, Hong Kong. 04/2022.
  4. JESSICA Most Successful Women Awards, Hong Kong South China Media, Hong Kong. 05/2021.
  5. Excellent Young Scientists Fund, National Natural Science Foundation of China, China. 09/2021.
  6. Young Investigator Award, CUHK East Meets West Symposium 2019, Hong Kong. 09/2019.
  7. For Women in Science: China Future Female Scientist Award and Hong Kong representative for the 2018 L’Oreal-UNESCO International Rising Talents Award, L’Oreal-UNESCO-China Association of Science and Technology, China. 01/2018.
  8. Alzheimer’s Association Research Fellowship, Alzheimer’s Association, USA. 10/2017-09/2021.
  9. Global Future Council Fellowship, World Economic Forum, Switzerland. 11/2016-11/2019.
  10. Junior Fellowship, HKUST Institute for Advanced Study, Hong Kong. 09/2015-06/2019.

Professional Services and Activities

  1. Official Nominator. VinFuture Prize. VinFuture Foundation, Vietnam. 01/2024-Current
  2. Grant reviewer. 深圳市医学研究专项资金. China. Since 09/2023-Current.
  3. Grant reviewer. Action for A-T. UK. Since 01/2022-Current.
  4. Journal reviewer. Academic journals including eNeuro, Aging Research Reviews, European Journal of Neuroscience, Genes & Diseases, BMC Biology, Laboratory Investigation, Frontiers of Neuroscience, Alzheimer’s Research and Therapy, Molecular Endocrinology. Since 09/2019-Current.
  5. Award reviewer. Trainee Professional Development Award (TPDA) Selection Committee, Society for Neuroscience, USA. 07/2019-12/2024 (Every year).
  6. Judge. ESF-Innofair 2022, English Schools Foundation, Hong Kong. 07/03/2022.
  7. Expert Panelist, Textbook Revision Study 2020, HKSAR Consumer Council, Hong Kong. 09/2020-10/2020.
  8. Chapter Representative, Hong Kong Society for Neuroscience (i.e., Hong Kong SAR Chapter), Society for Neuroscience, 09/2021-Current.

Teaching

 I. Classroom Teaching Courses

  1. BCHE4040 Aspects of Neuroscience (UG/ Fall Semester)
  2. FNSC3030 Nutritional Biochemistry (UG/ Fall Semester)
  3. FNSC5220 Nutrition and immunity across the Life Span (PG/ Fall Semester)
  4. BBMS6500 Research Methods and Literature Review in Biochemical and Biomedical Sciences (PG/ Fall Semester)
  5. BBMS5100 Perspectives in Biochemical Sciences (PG/ Fall Semester)
  6. LSCI6000 Research Methods and Ethics (PG/ Fall Semester)
  7. FNSC2002 Nutrition for Health (UG/ Spring Semester)
  8. ENSC3520 Environmental and Biochemical Toxicology (UG/ Spring Semester)
  9. BIOL4310 Human Genetics (UG/ Spring Semester)
  10. BMS5220 Biochemical and Biomedical Technology (PG/ Spring Semester)
  11. FNSC5320 Nutritional Physiology (PG/ Spring Semester)
  12. LSCI6302 Techniques in Transgenic Animals (PG/ Spring Semester)
  13. LSCI6301 Techniques in Mammalian Cell Research (PG/ Summer Semester)
       

 II. Dissertation/ Research Project Supervision Courses

  1. CBMI3100 Methodology of Critical Thinking in CMB (UG/ Fall Semester)
  2. BBMS6200 MSc Project (PG/ Fall Semester)
  3. FNSC6313 Directed Research and Seminar I  (PG/ Fall Semester)
  4. LSCI4902 Senior Experimental Project II (UG/ Fall Semester)
  5. FNSC6413 Directed Research and Seminar II (PG/ Spring Semester)
  6. CMBI3200 Proposal Formulation and Creative Scientific Writing in CMB (UG/ Spring Semester)
  7. LSCI4903 Senior Experimental Project III (UG/ Spring Semester)
       

Knowledge Exchanges, Community Engagement and Advocacy

  1. Health Policy Fellow in Committee on Research Priorities for Preventing and Treating Alzheimer’s Disease and Related Dementias, National Academy of Medicine, United States. 01/2024-12/2024 (Recommendation: Preventing and Treating Dementia: Research Priorities to Accelerate Progress 2024: https://nap.nationalacademies.org/catalog/28588/preventing-and-treating-dementia-research-priorities-to-accelerate-progress)
  2. Workshop organizer and program consultant. Curriculum of Cell Biology-related Drug Education Workshops of STEM Education Anti-drug Programme. Centre for Creative Science and Technology, The Hong Kong Federation of Youth Groups. Hong Kong. 09/2023-07/2024. (Recognized by the Education Bureau of HKSAR Government as a part of the requirement training of Continuing Professional Development of Teachers)
  3. Public lecture speaker. Title: How neuroscience is related to anti-drug education? The case study of Ketamine. STEAM Anti-drug Education Sharing Conference. The Hong Kong Federation of Youth Groups. Hong Kong. 26/06/2023.
  4. Public workshop speaker and demonstrator. STEAM Anti-drug Teachers Training Workshop: Forensic Toxicology and Neuroscience. The Hong Kong Federation of Youth Groups. 23/05/2023.
  5. Press release. Title: CUHK Team develops a big data analysis method to study senescent neurons. Providing new directions for precision medicine in neurodegenerative diseases. Communications and Public Relations Office. CUHK. Hong Kong. 15/03/2023.
  6. Press release. Title: CUHK study shows enhanced insulin-regulated immune function supports extreme health span and longevity. Communications and Public Relations Office. CUHK. Hong Kong. 15/03/2023.
  7. High school students laboratory visit host and lecture speaker. Exploring New Horizons 2023. Hong Kong Laurate Forum, Hong Kong. 11/03/2023.
  8. Featured scientist speaker. Women in Science—Yes We Can! Diversity and Inclusion Event, Faculty of Science, CUHK, Hong Kong. 02/12/2022.
  9. Workshop organizer and program consultant. Curriculum of Neuroscience-related Drug Education Workshops of STEM Education Anti-drugs Programme, Centre for Creative Science and Technology, The Hong Kong Federation of Youth Groups. Hong Kong. 09/2021-07/2022. (Recognized by the Education Bureau of HKSAR Government as a part of the requirement training of Continuing Professional Development of Teachers)
  10. Guest host and featured female scientist speaker. “Wonder Women in Science: Inspiring and Empowering the Next Generation”, Hong Kong Laurate Forum, Hong Kong. 26/07/2022. (https://fb.watch/e_GIfiiCYP/)
  11. Featured female scientist speaker. “凝聚香港 第二十七集 科學界女強人” RTHK 32, 26/07/2022. (https://www.youtube.com/watch?v=68e2It7bYGc)
  12. Featured female scientist speaker. “她力量 · 全球疫情背景下的女性科创力量”L’Oreal Hong Kong and Phoenix TV Forum. 19/07/2022 (1.23 Million views) (https://flive.ifeng.com/live/1008225.html?isFull=1&webkit=1&immersion=true&needpage=1&aman=65J4bbWb57f639m1b9R8a0S32471cbibf9416a2be5)
  13. Featured Scientist Wen Wei Po Newspaper Interview. Hong Kong. 12/2021. (https://dw-media.tkww.hk/epaper/wwp/20211228/a10-1228.pdf)
  14. Public lecture speaker. Title: From Understanding Simple Algae Protein to Complex Brain Science: The Story behind Optogenetics. Zoom into Science 2022 Lecture Series. Faculty of Science, CUHK. Hong Kong. 13/04/2022.
  15. Gifted high school student mentor, Gifted Education Fund, Off-school Advanced Learning Programmes for Gifted Students, HKSAR Education Bureau, Hong Kong. 06/2021-12/2021. (Mentee: Mr. Ishraq Farhan, Le Salle College)
  16. Press release. Title: CUHK Uncovers that Brain Cells in Alzheimer’s Patient Consumes Nutrition Essential to Neurotransmission. Study Supports Great Potential of Nutrient-based Approach in Managing Neurodegenerative Disorders. Communications and Public Relations Office. CUHK. Hong Kong. 22/07/2021.
  17. Public lecture speaker. Title: Hepatitis C—A Success Story from Being Unknown to Having a Cure. Host: Popular Science Special Lecture Series: How Nobel Prizes Are Won 2020, Faculty of Science, CUHK, Hong Kong. 04/12/2020.
  18. Public lecture speaker. Title: With DNA repair: double loss (break) is not scary at all (DNA 自修室:雙失不可怕). Host: Introductory Lecture for The Shaw Prize Lecture in Life Science and Medicine 2019, Shaw College, CUHK, Hong Kong. 19/09/2019.
  19. Featured scientist. Career Feature: “How to build a lab in East Asia’s science hot spots”. Nature. (https://www.nature.com/articles/d41586-018-05513-2?utm_source=fbk_nnc&utm_medium=social&utm_campaign=naturenews&sf192841411=1)
  20. Volunteer science policy advocate. Capitol Hill Day 2018, Society for Neuroscience. Washington, District of Columbia, USA. 03/2018. (https://neuronline.sfn.org/advocacy/if-you-get-involved-in-science-advocacy-heres-the-impact-you-can-make/)

 

Address

(Office): Rm LG89, Science Centre South Block

(Lab): Rm LG90, Science Centre South Block

 People TBC
 

Phone

(Office): (852) 3943 1272

(Lab): (852) 3943 1214
Fax (852) 2603 6382
Email This email address is being protected from spambots. You need JavaScript enabled to view it.
Web -

 

Education

1997 Ph.D., University of Florida
1987 M.Sc., Lanzhou University
1984 B.Sc., Lanzhou University

Position

  • Research Associate Professor, School of Life Sciences
  • Principal Investigator, State Key Lab of Agricultural Biotechnology

Research Interests

  • Molecular and genetic analysis of seed development in maize
  • Carotenoid metabolism and vitamin A fortification in crop seeds
  • Regulation of ABA biosynthesis under biotic and abiotic stresses

Representative Publications

  • Liu Y, Xiu ZH, Meeley R, Tan BC*. (2013) Empty pericarp5 encodes a pentatricopeptide repeat protein that is required for mitochondrial RNA editing and seed development in maize. Plant Cell 25: 868-883.
  • Shen Y., Li C, Meeley R, McCarty DR, Tan BC*. (2013) Embryo defective12 encodes translation initiation factor3 and is essential to maize embryogenesis. Plant J. 74: 792-804.
  • Zhang YF, Hou MM, Tan BC*. (2013) The requirement of WHIRLY1 for embryogenesis is dependent on genetic background in maize. PLoS One 8(6): e67369.
  • Tan BC*, Chen Z, Shen Y, Zhang Y, Lai J, Sun SSM. (2011) Identification of an active new Mutator transposable element in maize. Genes Genomes Genetics 1:293-302.
  • Messing SA, Gabelli SB, Echeverria I, Vogel, JT, Guan JC. Tan BC, Klee HJ, McCarty DR, Amzel LM*. (2010) Structural insights into maize Viviparous14, a key enzyme in the biosynthesis of the phytohormone abscisic acid. Plant Cell 22: 2970-2980.
  • Vogel JT, Tan BC, McCarty DR, Klee HJ*. (2008) The carotenoid cleavage dioxygenase 1 enzyme has broad substrate specificity, cleaving multiple carotenoids at two different bond positions. J. Biol. Chem. 283: 11364-1137.
  • Tan BC*, Joseph LM, Deng WT, Liu LJ, Li QB, Cline K, McCarty DR. (2003) Molecular characterization of the Arabidopsis nine-cis expoxycarotenoid dioxygenase gene family. Plant J. 35: 44-56.
  • Tan BC*, Cline K, McCarty DR. (2001) Localization and targeting of VP14 epoxy-carotenoid dioxygenase to the chloroplast membrane. Plant J. 27: 373-382.
  • Tan BC, Schwartz S, Zeevaart JA, McCarty DR*. (1997) Genetic control of abscisic acid synthesis in maize. Proc. Natl. Acad. Sci. USA 94: 12235-12240.
  • Schwartz S, Tan BC (Co-first author), Gage DA, Zeevaart JA, McCarty DR*. (1997) Specific oxidative cleavage of carotenoids by VP14 of maize. Science 276, 1872-1875.

Research Grants

  • 2014-2016, Research Grants Council, GRF. "Functional analysis of SMALL KERNEL 11 and identification of its interacting proteins". (PI, HK$ 736,128).
  • 2013-2015, Research Grants Council, GRF. "Functional analysis of Empty pericarp 5 in maize seed development". (PI, HK$ 890,000).
  • 2012-2014, Research Grants Council, GRF. "Functional analysis of EMB15 in maize seed development". (PI, HK$ 1,265,000).
  • 2010-2012, Research Grants Council, GRF, "Genetic and functional dissection of Emb12 and Emb14 in maize embryo development", (PI, HK$1,724,595).
  • 2012-2015, National Science Foundation of China, "Cloning and functional analysis of Small kernel2 gene in maize". (PI, RMB 550,000).
  • 2012-2016, Shenzhen Peacock Scheme, "Applied research of plant molecular biotechnology on modern agriculture". (Co-PI, RMB 30,000,000).
  • 2012-2015, CUHK Shenzhen Research Institute Start-up Support Scheme, "Functional analysis of SMK2 in maize". (PI, HK$ 250,000).
  • 2009-2011, China Transgenic Initiative, Sub-project: Identification and mechanistic study of genes related to crop yield, nutrition and stress resistance", (PI, RMB500,000; HK$700,000).
  • 2008-2011, Area of Excellence Scheme, Sub-project: Functional genomics of seed development in maize and rice. (PI, HK$1,650,000).
  • 2005-2008, National Science Foundation (USA), Functional analysis of plant carotenoid dioxygenases", (Co-PI, US$600,000).

Professional Activities

  • Editorial Board, Bulletin of Botany
  • Member of the International Association for Plant Biotechnology (IAPB)

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Address

(Office): Rm G78, Science Centre South Block

(Lab): LG 105, Run Run Shaw Science Building

 People WYS
 

Phone

(Office): (852) 3943 6148

(Lab): (852) 3943 6280
Fax (852) 2603 5646
Email This email address is being protected from spambots. You need JavaScript enabled to view it.
Web -
 

 

Education

1976 Ph.D. University of Hong Kong
1973 B.Sc. University of Hong Kong

Position

  • Research Professor, School of Life Sciences

Research Interests

  • Fish osmoregulatory physiology
  • Biology of stress and heat stock proteins
  • Fish diseases

Representative Publications

  • Deane, E. E., Luk, J. C. Y. and Woo, N. Y. S. (2011) Aquaporin 1a expression in gill, intestine and kidney of the euryhaline silver sea bream. Frontiers in Physiology 2: 39 doi: 10.3389/fphys.2011.00039
  • Deane, E. E. and Woo, N. Y. S. (2011) Advances and perspectives on the regulation and expression of piscine heat shock proteins. Reviews in Fish Biology and Fisheries 21: 153-185.
  • Leung, L. Y., and Woo, N. Y. S. (2010) Effects of growth hormone, insulin-like growth factor I, triiodothyronine, thyroxine, and cortisol on gene expression of carbohydrate metabolic enzymes in sea bream hepatocytes. Comparative Biochemistry and Physiology A157: 272-282.
  • Jia, A., Woo, N. Y. S., and Zhang, X.-H. (2010) Expression, purification and characterization of thermolabile hemolysin (TLH) from Vibrio alginolyticus. Diseases of Aquatic Organisms90: 121-127.
  • Bai, F., Sun, B., Woo, N. Y. S., and Zhang, X-H (2010) Vibrio harveyi hemolysin induces ultrastructural changes and apoptosis in flounder (Paralichthys olivaceus) cells. Biochemical and Biophysical Research Communications395: 70-75.
  • Deane, E. E. and Woo, N. Y. S. (2009) Modulation of fish growth hormone levels by salinity, temperature, pollutants and aquaculture related stress: a review. Reviews in Fish Biology and Fisheries 19: 97-120.
  • Kwong, A. K. Y. and Woo, N. Y. S. (2008) Prolactin-releasing peptide, a possible modulator of prolactin in the euryhaline silver sea bream (Sparus sarba): a molecular study. General and Comparative Endocrinology 158: 154-160.
  • Man, A. K. Y. and Woo, N. Y. S. (2008) Upregulation of metallothionein and glucose-6-dehydrogenase expression in silver sea bream, Sparus sarba, exposed to sublethal levels of cadmium. Aquatic Toxicology 89: 214-221.
  • Deane, E. E., Zhou, L. R. and Woo, N. Y. S. (2006) Cortisol can be pro- or anti-apoptotic in sea bream cells: potential role of HSP70 induction for cytoprotection. Molecular and Cellular Endocrinology 259: 57-64.
  • Deane, E. E. and Woo, N. Y. S. (2006) Tissue distribution, effects of salinity acclimation and ontogeny of aquaporin 3 in the marine teleost silver sea bream (Sparus sarba). Marine Biotechnology 8: 663-671.

Research Grants

  • 2011-2013: RGC GRF, Function and regulation of cystic fibrosis transmembrane regulator (CFTR) in gill and intestine of the euryhaline seabream. PI. $690,000
  • 2009-2012: RGC GRF: Do salinity and hormones influence apoptosis and transformation of gill chloride cells? PI, $1,636,666.
  • 2005-2008: RGC Earmarked Grant: Molecular strategies of temperature acclimation in the sea bream. PI, $815,957.
  • 2003-2006: RGC Earmarked Grant: Role of aquaporin water channels in the osmoregulatory strategy of the euryhaline marine teleost Sparus sarba. PI: $1,388,000.
  • 2002-2005: RGC Earmarked Grant: Growth hormone and insulin-like growth factor – I as anti-apoptotic factors via modulated HSP70 expression in sea bream. PI: $1,354,000.
  • 2001-2004 RGC Earmarked Grant: Stimulation of glucose-6-phosphate dehydrogenase activity in sea bream: metabolic significance and potential applications. PI: $1,078,000.
  • 2000-2002 RGC Earmarked Grant: Modulation of gill Na+-K+-ATPase expression by salinity and hormonal factors in the sea bream, Sparus sarba. PI: $679,200.
  • 1999 – 2002 RGC Earmarked Grant: Protective effects of heat shock protein 70 (HSP70) against environmental and pathogenic stress in the marine teleost Sparus sarba. PI: $920,640.
  • 1998-2000 RGC Earmarked Grant: Enhancing immunological competence of silver sea bream (Sparus sarba) through the combined application of salinity adaptation, hormonal factors and specific vaccines. PI: $645,000.
  • 1997-2000: RGC Earmarked Grant: Evaluation of novel microencapsulated formulations for the improved survival and development of cultured marine fish larvae. PI: $849,500.
  • 1995-1997: RGC Earmarked Grant: An iso‑osmotic marine fish factory. PI: $531,000.
  • 1991-1994: RGC Earmarked Grant: An assessment of the feasibility of developing ‘factory‑based' marine fish culture. PI; $400,000.
  • 2004-2009: Area of Excellence (AoE): Centre for Marine Environmental Research and Innovative Technology (MERIT): $925,000.
  • 2009-2012: Area of Excellence (AoE) Extension: Centre for Marine Environmental Research and Innovative Technology (MERIT): $300,000.
  • 2009-2011: NSFC-RGC Joint Research Scheme: Elucidation of the role played by Vibrio virulence factors on cytoprotection and apoptosis in fish cells. PI: $656,400.

 Awards

  • Ocean Services Award, PACON International, USA
  • Distinguished Member Award, PACON International, USA

Professional Activities

  • Editorial Board, Frontiers in Aquatic Physiology
  • Editorial Board, Journal of Marine Biology
  • Editorial Board, Open Marine Biology Journal

Others

  • Partner Laboratory - State Key Laboratory in Marine Pollution