Dr PANG Kok Shuen Iris

Address

(Office): Rm 138, Science Centre North Block
(Lab): --

 People PKS
 

Phone

(Office): (852) 3943 1393
(Lab): --
Fax

(852) 2603 6510
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Web --
 

 

Education

Ph.D. Yale University
B.S. University of Washington

 

Position

  • Lecturer, School of Life Sciences


Research Interests

  • Immunology
  • Innate activation of adaptive immunity
  • Pathogen recognition by innate receptors
  • Influenza virus infection
  • Immune regulation by commensal bacteria


Representative Publications

  • Li L., Leung A.K., Kwok T.P., Lai Y.Y.Y., Pang I.K., Chung G.T., Mak A.C.Y., Poon A., Chu C., Li M., Wu J.J.K., Lam E.T., Cao H., Lin C., Sibert J., Yiu S.M., Xiao M., Lo K.W., Kwok P.Y., Chan T.F., Yip K.Y. (2017). OMSV enables accurate and comprehensive identification of large structural variations from nanochannel-based single-molecule optical maps. Genome Biol. 18(1):230.
  • Schmid E.T., Pang I.K., Carrera Silva E.A., Bosurgi L., Miner J.J., Diamond M.S., Iwasaki A., Rothlin C.V. (2016). AXL receptor tyrosine kinase is required for T cell priming and antiviral immunity. Elife. 5:e12414.
  • Pillai P.S., Molony R.D., Martinod K., Dong H., Pang I.K., Tal M.C., Solis A.G., Bielecki P., Mohanty S., Trentalange M., Homer R.J., Flavell R.A., Wagner D.D., Montgomery R.R., Shaw A.C., Staeheli P., Iwasaki A. (2016). Mx1 reveals innate pathways to antiviral resistance and lethal influenza disease. Science. 352(6284):463-6.
  • Pang, I.K., Pillai, P.S., and Iwasaki, A. (2013). Efficient influenza A virus replication in the respiratory tract requires signals from TLR7 and RIG-I. Proc Natl Acad Sci U S A. 110(34), 13910-5.
  • Pang, I.K., Ichinohe, T., and Iwasaki, A. (2013). IL-1R signaling in dendritic cells replaces pattern-recognition receptors in promoting CD8(+) T cell responses to influenza A virus. Nature immunology 14, 246-253.
  • Pang, I.K., and Iwasaki, A. (2012). Control of antiviral immunity by pattern recognition and the microbiome. Immunological Reviews 245, 209-226.
  • Ichinohe, T.*, Pang, I.K.*, Kumamoto, Y., Peaper, D.R., Ho, J.H., Murray, T.S., and Iwasaki, A. (2011). Microbiota regulates immune defense against respiratory tract influenza A virus infection. Proc Natl Acad Sci U S A 108(13), 5354-5359. *, authors contributed equally to this work
  • Pang, I.K., and Iwasaki, A. (2011). Inflammasomes as mediators of immunity against influenza virus. Trends in immunology 32, 34-41.
  • Ichinohe, T., Pang, I.K., and Iwasaki, A. (2010). Influenza virus activates inflammasomes via its intracellular M2 ion channel. Nature immunology 11, 404-410.

 
Awards

  • Faculty Exemplary Teaching Award, Faculty of Science, CUHK, 2016
  • Distinguished Doctoral Dissertation, Yale University Graduate School of Arts and Sciences, 2013
  • Distinguished Speaker Award, Yale University Microbial Diversity Institute Symposium, 2012
  • Keystone Symposia Travel Scholarship, 2011
  • Amgen Scholars Alumni Travel Award, 2011

 
Professional Activities

  • Speaker, “Taking brakes off Immune System to attack Cancer”, Popular Science Special Lecture Series: How Nobel Prizes Are Won, Faculty of Science, CUHK, 2018
  • Speaker, “Ebola: The Micro-Killer”, The 11th Lau Oi Wah Memorial Science Lecture Series, Faculty of Science, CUHK, 2015
  • Invited Speaker, 6th HKU-Pasteur Immunology Course for Research Postgraduate Students, 2013
  • Invited Workshop Presenter, Keystone Symposia Conference on Pathogenesis of Influenza, 2011