Professor CHEUNG Chi Keung Peter

Address

(Office): EG09, Science Centre East Block
(Lab): Rm 381, Science Centre South Block

 People CCK 

Phone

(Office): (852) 3943 6144
(Lab): (852) 3943 6272
Fax (852) 2603 5646
Email This email address is being protected from spambots. You need JavaScript enabled to view it.
Web http://www.cuhk.edu.hk/lifesciences/aboutus/people/CCK.html
 

 


Education

Ph.D. University of New South Wales
M.Chem. University of New South Wales
B.Sc. The University of Hong Kong


Position

  • Professor, School of Life Sciences
  • Associate Director of Food and Nutritional Sciences Program
  • Director of Food Research Centre
  • Head, The Graduate Division, School of Life Sciences, CUHK


Research Interests

  • Structure-function of cell wall polysaccharides
  • Bioactive carbohydrates from mushroom and edible fungi
  • Chemical properties and biological functions of beta-glucans
  • Prebiotics, probiotics and gut microbiome
  • Polysaccharides as nano complexing agent for targeted drug delivery


Representative Publications (Past five years)

  1. Zhang, B., Guan, Y., Hu, P., Chen, L., Xu, G., Liu, L. and Cheung, P.C.K. (2019). Production of bioactive metabolites by submerged fermentation of the medicinal mushroom Antrodia cinnamomea: recent advances and future development. Critical Reviews in Biotechnology, 39, 541-554. https://doi.org/10.1080/07388551.2019.1577798
  2. Ke, X., Walker, A., Haange, S.-B., Lagkouvardos, I., Liu, Y., Schmitt-Kopplin, P., von Bergen, M., Jehmlich, N., He, X., Clavel, T., and Cheung, P.C.K. (2019). Synbiotic-driven improvement of metabolic disturbances is associated with changes in the gut microbiome in diet-induced obese mice. Molecular Metabolism, 22, 96-109. https//doi.org/1016/j.molmet.2019.01.012
  3. Lam, K.L., Ko, K.C., Li, X., Ke, X., Cheng, W.Y., Chen, T.F., You, L., Kwan, H.S. and Cheung, P.C.K. (2019). In vitro infant fecal fermentation of low viscosity barley beta-glucan and its acid hydrolyzed derivatives: Evaluation of their potential as novel prebiotics. Molecules, 24, 828. https://doi.org/10.3390/molecules24050828
  4. Huang, S., Pang, D., Li, X., You, L., Zhao, Z., Cheung, P.C.K., Zhang, M. and Liu, D. (2019). A sulfated polysaccharide from Gracilaria lemaneiformis regulate cholesterol and bile acid metabolism in high-fat diet mice. Food and Function, 10, 3224-3236. https://doi.org/1039/C9FO00263D
  5. Chen, X., Li, X., Zhang, X., You, L., Cheung, P.C.K., Huang, R. and Xiao, J. (2019). Antihyperglycemic and antihyperlipidemic activities of a polysaccharide from Physalis pubescens in streptozotocin (STZ)-induced diabetic mice. Food and Function, 10, 4868-4876. https://doi.org/10.1039/C9FO00687G
  6. Chen, L., Ge, M., Zhu, Y., Song, Y., Cheung, P.C.K., Zhang, B., Liu, L. (2019). Structure, bioactivity and applications of natural hyperbranched polysaccharides. Carbohydrate Polymers, 223, 115076. https://doi.org/10.1016/j.carbpol.2019.115076
  7. Liu, C. and Cheung, P.C.K. (2019). Structure and immunomodulatory activity of microparticulate mushroom sclerotial β-glucan prepared from Polyporus rhinocerus. Journal of Agricultural and Food Chemistry, 67, 9070-9078. https://doi.org/10.1021/acs.jafc.9b03206
  8. Tang, H.M. and Cheung, P.C.K. (2019). Gallic acid triggers iron-dependent cell death with apoptotic, ferroptotic, and necroptotic features. Toxins, 11, 492. https://doi.org/3390/toxins11090492
  9. Javed, S., Li, W.M., Yaqoob, A., Zeb, M., Tackaberry, L., Massicotte, H., Egger, K., Cheung, P.C.K., Payne, G. and Lee, C.H. (2019). Anti-inflammatory activity of the wild mushroom, Echinodontium tinctorium, in RAW264.7 macrophage cells and mouse microcirculation. Molecules, 24, 3509 https://doi.org/3390/molecules24193509
  10. Liu, C., Choi, M.W. and Cheung, P.C.K. (2019). Immunomodulatory effect of structurally characterized mushroom sclerotial polysaccharides isolated from Polyporus rhinocerus on bone marrow dendritic cells. Journal of Agricultural and Food Chemistry, 67, 12137-12143. https://doi.org/10.1021/acs.jafc.9b03294
  11. Lam, K.L. and Cheung, P.C.K. (2019). Carbohydrate-based prebiotics in targeted modulation of gut microbiome. Journal of Agricultural and Food Chemistry, 67, 12335-12340. https://doi.org/10.1021/acs.jafc.9b04811
  12. Li, X. and Cheung, P.C.K. (2019). Application of natural beta–glucans as biocompatible functional nanomaterials. Food Science and Human Wellness, 8, 315-319. https://doi.org/10.1016/j.fshw.2019.11.005
  13. Chen, J., Fang, L., Wu, S., Tang, S., Cheung, P.C.K., Li, H. and Wu, X. (2019). Detection of norovirus genogroup II in lecture by droplet digital PCR. Food Science, 40, 332-337.
  14. Lam, K.L., Cheng, W.Y., Yang, F., Lin, S., You, L., Chiou, J., Kwan, H.S. and Cheung, P.C.K. (2020). Framework as a service, FaaS: personalized prebiotic development for infants with the elements of time and parametric modelling of in vitro Fermentation. Microorganisms, 8(5), 623. https://doi.org/10.3390/microorganisms8050623
  15. Lam, K.L., Cheng, W.Y., Su, Y., Li, X., Wu, X., Wong, K.H., Kwan, H.S. and Cheung, P.C.K. (2020). Use of random forest analysis to quantify the importance of the structural characteristics of beta-glucans for prebiotic development. Food Hydrocolloids, 108, https://doi.org/10.1016/j.foodhyd.2020.106001
  16. Su, Y., Li, X., Lam, K.L. and Cheung, P.C.K. (2020). pH-sensitive PEG-coated hyper-branched β-glucan derivative as carrier for CpG oligodeoxynucleotide delivery. Carbohydrate Polymers, 246, https://doi.org/10.1016/j.carbpol.2020.116621
  17. Cheng, W.Y., Lam, K.L., Kong, A.P.S., and Cheung, P.C.K. (2020). Prebiotic supplementation (beta-glucan and inulin) attenuates circadian misalignment induced by shifted light-dark cycle in mice by modulating circadian gene expression. Food Research International, 137, 109437. https://doi.org/10.1016/j.foodres.2020.109437
  18. Lau, A.Y.T., Xie, Y., Cheung, M.K., Cheung, P.C.K. and Kwan, H.S. (2020) Genome-wide mRNA and miRNA analysis in the early stages of germ tube outgrowth in Coprinopsis cinerea. Fungal Genetics and Biology, 142, 103416. https//doi.org/1016/j.fgb.2020.103416
  19. Lam, K.L., Wu, J., Di, W., Chen, G. and Cheung, P.C.K. (2020). 2020s: the homecoming decade of high-throughput investigation of polysaccharides. Journal of Agricultural and Food Chemistry, 68, 8511-8513. http://doi.org/10.1021/acs.jafc.0c04286
  20. Sum, A.Y.C., Li, X., Yeng, Y.Y.H., Razif, M.F.M., Jamil, A.H.A., Ng S.T., Tan, C.S., Cheung, P.C.K. and Fung, S.Y. (2020). The immunomodulating properties of Tiger Milk medicinal mushroom Lignosus rhinocerus TM02® cultivar (Agaricomycetes) and its associated carbohydrate composition. International Journal of Medicinal Mushrooms, 22, 803-814. DOI:1615/IntJMedMushrooms.2020035658
  21. Huang, J.J. Huang, W., Li, J., Li, P. and Cheung, P.C.K. (2020). Potential advancement of ultraviolet-free solar radiation technology in enriching the nutrient composition and biodiesel feedstock production in marine green microalga Platymonas subcordiformis. Bioresource Technology Reports, 11, 100534. https://doi.org/10.1016/j.biteb.2020.100534
  22. Lin, S., Wang, P., Li, S., Lam, K.L., Hu, J., Cheung, P.C.K. (2020). Recent research on specialty mushroom (Pleurotus tuber-regium) as functional food: Chemical composition and biological activities. Journal of Agricultural and Food Chemistry, 68, 9277-9286. https://doi.org/10.1021/acs.jafc.0c03502
  23. Sum, A.Y.C., Li, X., Yeng, Y.Y.H., Razif, M.F.M., Jamil, A.H.A., Ng, S.T., Tan, C.S., Cheung, P.C.K. and Fung, S.Y. (2020). Immunomodulatory properties of water-soluble polysaccharides extracted from the fruiting body of Ophiocordyceps sinensis cultivar OCS02® (Ascomycetes). International Journal of Medicinal Mushrooms, 22, 967-977. https//doi.org/1615/IntJMedMushrooms.2020036351
  24. Su, Y., Chen, L., Yang, F. and Cheung, P.C.K. (2021). β-D-glucan based drug delivery system and its potential application in targeting tumor associated macrophages. Carbohydrate Polymers, 253, 117258. https://doi.org/10.1016/j.carbpol.2020.117258
  25. Zhang, Y., You, L., Cheung, P.C.K., Liao, L. and Zhao, Z. (2021). Behavior of non-digestible polysaccharides in gastrointestinal tract: a mechanistic review of its anti-obesity effect. eFood, 2, 59-72. https://doi.org/10.2991/efood.k.210310.001
  26. Huang, J.J. and Cheung, P.C.K. (2021). Cold stress treatment enhances production of metabolites and biodiesel feedstock in Porphyridium cruentum via adjustment of cell membrane fluidity. Science of the Total Environment, 780, 146612. https://doi.org/10.1016/j.scitotenv.2021.146612
  27. Gong, Y., Ma, Y., Cheung, P.C.K., You, L., Liao, L., Pedisic, S. and Kulikouskaya, V. (2021). Structural characteristics and anti-inflammatory activity of UV/H2O2-treated algal sulfated polysaccharide from Gracilaria lemaneiformis. Food and Chemical Toxicology, 152, 112157. https://doi.org/1016/j.fct.2021.112157
  28. Cheng, W.Y., Lam, K.L., Li, X., Kong, A.P.S and Cheung, P.C.K. (2021). Circadian disruption-induced metabolic syndrome in mice is ameliorated by oat β-glucan mediated by gut microbiota. Carbohydrate Polymers, 267, 118216. https://doi.org/10.1016/j.carbpol.2021.118216
  29. Tang, H.M. and Cheung, P.C.K. (2021). Gene expression profile analysis of gallic acid-induced cell death process. Scientific Reports, 11, https://doi.org/10.1038/s41598-021-96174-1
  30. Leung, M.F. and Cheung, P.C.K. (2021). Vitamin D and D2 in cultivated mushrooms under UV-irradiation and its bioavailability in humans: A mini-review. International Journal of Medicinal Mushrooms, 23, 1-15. https://doi.org/1615/IntJMedMushrooms.2021040390
  31. Hu, Y., Ge, M., Sun, D., Chen, L., Cheung, P.C.K., You, C., Chen, X., Sun, M. and Ng, H. (2022). Stimulating mechanism of corn oil on biomass and polysaccharide production of Pleurotus tuber-regium. International Journal of Biological Macromolecules, 201, 93-103. https://doi.org/10.1016/j.ijbiomac.2021.12.149
  32. Tang, L.,Sun, Y., Ge, P., Chen, L., Cheung, P.C.K., Ding, Z. and Fang, J. (2022). Biogenetic nanocarriers with enhanced pH stability formed by zein and selectively depolymerized mushroom hyperbranched β-glucans. International Journal of Biological Macromolecules, 209, Part B 1771-1783. https://doi.org/10.1016/j.ijbiomac.2022.04.147
  33. Hu, J., Yao, W., Chang, S., You, L., Zhao, M., Cheung, P.C.K. and Hileuskaya, K. (2022). Structural characterization and anti-photoaging activity of a polysaccharide from Sargassum fusiforme. Food Research International, 157, 111267. https://doi.org/10.1016/j.foodres.2022.111267
  34. Li, X., Peng, B., Cheung, P.C.K., Wang, J., Zheng, X. and You, L. (2022). Depolymerized non-digestible sulfated algal polysaccharides produced by hydrothermal treatment with enhanced bacterial fermentation characteristics. Food Hydrocolloids, 130, 107687. https://doi.org/10.1016/j.foodhyd.2022.107687
  35. Huang, W., Chen, Y., Hu, J., Yao, W., You, L. and Cheung, P.C.K. (2022). Algal sulfated polysaccharide-based hydrogels enhance gelling properties and in vitro wound healing compared to conventional hydrogels. Algal Research, 65, 102740. https://doi.org/10.1016/j.algal.2022.102740
  36. Su, Y., Yang, F., Chen, L. and Cheung, P.C.K. (2022). Mushroom carboxymethylated β-D-glucan functions as a macrophage-targeting carrier for IONPs and an inducer of proinflammatory macrophage polarization for immunotherapy. Journal of Agricultural and Food Chemistry, 70, 7110–7121. http://doi.org/10.1021/acs.jafc.2c01710
  37. Chan, P.L., Lauw, S., Ma, K.L., Kei, N., Ma, K.L., Wong, Y.O., Lam, H.Y., Ting, Y.Y., Yau, T.K., Nong, W., Huang, D., Xie, Y., Cheung, P.C.K. and Kwan, H.S. (2022). ProBioQuest: a database and semantic analysis engine for literature, clinical trials and patents related to probiotics. Database, 2022, baac059. DOI: https://doi.org/10.1093/database/baac059
  38. Tam, L.K.B., He, L., Ng, D.K.P., Cheung, P.C.K., Lo, P. (2022). A tumor-targeting dual-stimuli-activatable photodynamic molecular beacon for precise photodynamic therapy. Chemistry – A European Journal. doi: 10.1002/chem.202201652
  39. Shi, J., Zhang, R., Liu, X., Zhang, Y., Du, Y., Dong, H., Ma, Y., Li, X., Cheung, P.C.K. and Chen, P. (2023). Advances in multifunctional biomass-derived nanocomposite films for active and sustainable food packaging. Carbohydrate Polymers, 301, 120323. https://doi.org/10.1016/j.carbpol.2022.120323
  40. Su, Y., Yang, F., Wang, M. and Cheung, P.C.K. (2023). Cancer immunotherapeutic effect of carboxymethylated β-D-glucan coupled with iron oxide nanoparticles via reprogramming Tumor-Associated Macrophages. International Journal of Biological Macromolecules, 228, 692-705. https://doi.org/10.1016/j.ijbiomac.2022.12.154
  41. Tam, L., Chu, J.C.H., He, L., Yang, C., Han, K.-C., Cheung, P.C.K., Ng, D. and Lo, P.-C. (2023). An enzyme-responsive double-locked photodynamic molecular beacon for targeted photodynamic anticancer therapy. Journal of the American Chemical Society, 145, 7361-7375. https://doi.org/10.1021/jacs.2c13732
  42. Yang, F. and Cheung, P.C.K. (2023). Fungal β-glucan-based nanotherapeutics: From fabrication to application. Journal of Fungi, 9, 475. https://doi.org/10.3390/jof9040475
  43. Yu, B., Wang, M., Teng, B., Veeraperumal, S., Cheung, P.C.K., Zhong, S. and Cheong, K.L. (2023). Partially acid-hydrolyzed porphyran improved dextran sulfate sodium-induced acute colitis by modulation of gut microbiota and enhancing mucosal barrier. Journal of Agricultural and Food Chemistry, 71, 7299-7311. https://doi.org/10.1021/acs.jafc.2c08564
  44. Tam, L.K.B., Lo, P.C., Cheung, P.C.K. and Ng, D.K.P. (2023). A tetrazine-caged carbon-dipyrromethene as a bioorthogonally activatable fluorescent probe. Chemistry - An Asian Journal, e202300562. https://doi.org/10.1002/asia.202300562
  45. Yao, W., Yong, J., Lv, B., Gun, S., You, L., Cheung, P.C.K. and Kulikouskaya, V.I. (2023). Enhanced in vitro anti-photoaging effect of degraded seaweed polysaccharides by UV/H2O2 treatment. Marine Drugs, 21, 430. https://doi.org/10.3390/md21080430
  46. Kei, N., Wong, V.W., Lauw, S., You, L. and Cheung, P.C.K. (2023). Utilization of food-derived β-glucans to prevent and treat Non-Alcoholic Fatty Liver Disease (NAFLD). Foods, 12, 3279. https://doi.org/10.3390/foods12173279
  47. Lauw, S., Kei, N., Chan, P.-L., Yau, T.-K., Ma, K.-L., Szeto, C. Y.-Y., Lin, J. S.-C., Wong, S. H., Cheung, P.C.K. and Kwan, H.S. (2023). Effects of synbiotic supplementation on metabolic syndrome traits and gut microbial profile among Hong Kong Chinese: A randomized trial. Nutrients, 15, 4248; https://doi.org/10.3390/nu15194248
  48. Yang, H., Hu, J., Tan, B.K., Wong, K.-H., Huang, J.J., Cheung, P.C.K. and Lin, S. (2023). Lesson learned from COVID-19 pandemic for the future of food industry. Heliyon, 9, e22479. https://doi.org/10.1016/j.heliyon.2023.e22479
  49. Ma, K.L., Kei, N., Yang, F., Lauw, S., Chan, P.L., Chen, L. and Cheung, P.C.K. (2023). In vitro fermentation characteristics of fungal polysaccharides derived from Wolfiporia cocos and their effect on fecal microbiota. Foods, 12, 4041. https://doi.org/10.3390/foods12214014
  50. Li, Y.-Z., S, J.-Y., Wu, H., Wong, K.-H., Cheung, P.C.K., Lv, X.-C., Yang, Q.-Q. and Zhang, B.-B. (2023). Effects of pomelo sponge fermented by Monascus ruber on cholesterol metabolism and intestinal microbiota in high-fat diet mice. Food Bioscience, 56, 103376. https://doi.org/10.1016/j.fbio.2023.103376
  51. Fan, J.-H., Xiang, L.-Q., Huang, W., Hong, J.-Q., Guo, H.-K., Wong, K.-H., Cheung, P.C.K., Yang, Q.-Q. and Zhang, BB. (2023). Exopolysaccharides produced by Antrodia cinnamomea using microparticle-enhanced cultivation: Optimization, primary structure and antibacterial property. International Journal of Biological Macromolecules, 259, 128872. https://doi.org/10.1016/j.ijbiomac.2023.128872
  52. Liu, J., Lam, K.L., Zhang, Z., Deng, Y., Cheung, P.C.K. and Chen, G. (2024). Correlation between aeration time in aerobic granular sludge reactors with the production of bioactive polysaccharides and microbial communities. Resource, Conservation and Recycling, 203, 107408. https://doi.org/10.1016/j.resconrec.2024.107408
  53. Kei, N., Cheung, K.K., Ma, K.L., Yau, T.K., Lauw, S., Wong, V.W.S., You, L. and Cheung, P.C.K. (2024). Effects of Oat β-glucan and inulin on alleviation of non-alcoholic steatohepatitis aggravated by circadian disruption in C57BL/6J mice. Journal of Agricultural and Food Chemistry, 72, 7, 3520-3535. https://doi.org/10.1021/acs.jafc.3c08028
  54. Luo, S., Wei, S.-M., Luo, X.-T., Yang, Q.-Q., Wong, K.-H., Cheung, P.C.K. and Zhang, B.B. (2024). How probiotics, prebiotics, synbiotics, and postbiotics prevent dental caries: an oral microbiota perspective. npj Biofilms and Microbiomes 10(1):14. doi: 10.1038/s41522-024-00488-7
  55. Zhu, B., Guo, S., Cheung, P.C.K., Hileuskaya, K. and You, L. (2024). Protection and delivery of probiotics by degraded fucoidan-chitosan nanogel-based W1/O/W2 double emulsion incorporated in self-assembled hydrogel particles. Food Hydrocolloids, 153, 109999. https://doi.org/10.1016/j.foodhyd.2024.109999
  56. Yang, F., Su, Y., Yan, C., Chen, T. and Cheung, P.C.K. (2024). Attenuation of inflammatory bowel disease by oral administration of mucoadhesive polydopamine-coated yeast β-glucan via ROS scavenging and gut microbiota regulation. Journal of Nanobiotechnology, 22:166. https://doi.org/10.1186/s12951-024-02434-3
  57. Chang, S., Chen, Y., Qiu, H., Zhu, B., You, L. and Cheung, P.C.K. (2024). The isolation, structure characterizations and anti-photoaging activities of sulfated polysaccharides isolated from Sargassum fusiforme. Chemical and Biological Technologies in Agriculture, 11:64. https://doi.org/10.1186/s40538-024-00587-9
  58. Huang, Y., Shi, J., Luo, X., Luo, S., Cheung, P.C.K., Corke, H., Yang, Q. and Zhang, B. (2024). How do probiotics alleviate constipation? A narrative review of mechanisms. Critical Reviews in Biotechnology 1-17. https://doi.org/10.1080/07388551.2024.2336531
  59. Zhuang, J., Zhu, J., Cheung, P.C.K. and Li, L. (2024). The physical and chemical interactions between starch and dietary fiber: Their impact on the physicochemical and nutritional properties of starch. Trends in Food Science and Technology, 149, 104566. https://doi.org/10.1016/j.tifs.2024.104566
  60. Huo, J., Zhu, B., Ma, C., You, L., Cheung, P.C.K., Pedisic, S. and Hileuskaya, K. (2024). Effects of chemically reactive species generated in plasma treatment on the physico-chemical properties and biological activities of polysaccharides: An overview. Carbohydrate Polymers, 342, 122361. https://doi.org/10.1016/j.carbpol.2024.122361
  61. Kei, N., Lauw, S., Wong, V.W.S. and Cheung, P.C.K. (2024). A mini-review on prebiotic inulin to prevent and treat non-alcoholic fatty liver disease. Food Bioscience, 61, 104679. https://doi.org/10.1016/j.fbio.2024.104679
  62. Huang, J., Xu, W., Lin, S. and Cheung, P.C.K. (2024). The bioactivities and biotechnological production approaches of carotenoids derived from microalgae and cyanobacteria. Critical Reviews in Biotechnology, https://doi.org/10.1080/07388551.2024.2359966


Research Grants 

  • 2023-2024, General Research Fund (GRF), Protective effects of prebiotic β-glucans on non-alcoholic steatohepatitis aggravated by circadian disruption in mice is mediated by gut microbiota and their metabolites HKD 1370972
  • 2023-2025, Guangdong Province International Science and Technology Cooperation Fund (ISTCF) Key technology and industrial application of high-efficiency preparation of seaweed polysaccharides RMB 2000000
  • 2021-2023, General Research Fund (GRF), Does dietary oxidized cholesterol alter gut microbiota and is it more atherosclerotic than dietary cholesterol itself? HKD 1,125,732
  • 2020-2024, Theme-based Research (TBR), A paradigm-shifting, fully-integrated, compact wastewater-to-resource facility – Chemical and biological properties of sulfated polysaccharides recovered from sludge. HKD 1,646,000
  • 2019-2024, Research Impact Fund (GIF), Tackling grand challenges in food safety: A bug data and IoT enabled approach HKD 790,160
  • 2018-2020, General Research Fund (GRF), Post-transcriptional modification of early stages of fruiting body development and alternate destinies of the model mushroom Coprinopsis cinerea. HKD 817,190
  • 2015-2016, General Research Fund (GRF), In vitro bifidogenicity of prebiotic mushroom beta-glucan and its effect on human gut microbiota: A mechanistic study using transcriptomics, fractional proteomics and 16S rDNA sequences. HKD 844,130
  • 2013-2014, General Research Fund (GRF), A comparative study of the in vitro immunomodulating effects of structurally well-defined purified mushroom and fungal beta-glucans in human immune cells. HKD 542,136
  • 2011-2012, General Research Fund (GRF), Ultrasonication-induced changes in the higher order structures of high molecular weight polysaccharides from medicinal fungi and their relationship to immunoactivity, HKD 710,000
  • 2009-2011, General Research Fund (GRF), Controlled degradation of high molecular weight polysaccharides from a medicinal fungus by ultrasonication for improvement of medicinal properties, HKD 620,000
  • 2006-2009, National Natural Science Foundation of China (NSFC), The effect of molecular dimension and solution conformation of mushroom polysaccharides with their biological activities and mechanisms, RMB 1,300,000
  • 2005-2007, Research Grants Council (RGC) Earmarked Grants, Mushroom non-digestible carbohydrates as novel β-glucan type prebiotics: Their preparation and in vitro microbial fermentation, HKD 718,957
  • 2002-2004, Research Grants Council (RGC) Earmarked Grants, A mechanistic study of the immunopotentiating and antitumor effects of native and chemically modified nonstarch polysaccharides [(1-3)-beta-D-glucans] from mushroom sclerotia, HKD 1,036,000
  • 2002-2004, Research Grants Council (RGC) Earmarked Grants, In vitro and in vivo anticancer studies of novel polyunsaturated fatty acids (DHA, EPA) purified and characterized from several enriched microalgae, HKD 876,000
  • 2002-2004, University Grants Council Area of Excellence (AoE) in Plant and Fungal Biotechnology, Immunopharmacological activities of native and chemically modified mushroom non-starch polysaccharides, HKD 500,000
  • 2000-2002, University Grants Council Area of Excellence (AoE) in Plant and Fungal Biotechnology, Isolation, characterization, bioassay and functional tests of mushroom polysaccharides with anti-tumor and immuno-potentiating activities, HKD 700,000
  • 1999-2001, Research Grants Council (RGC) Earmarked Grants, Correlation between antitumor activities and structural characteristics of mushroom polysaccharides HKD 580,000
  • 1999-2004, Strategic Grant of the Chinese University of Hong Kong, Pharmaceutical, nutritional and biotechnological application of seaweed resources in Hong Kong HKD 600,000
  • 1996-1998, Research Grants Council (RGC) Earmarked Grants, Characterization of pharmacologically active substances and nutritional evaluation of selected seaweeds in Hong Kong, HKD 500,000


Patents

  • The preparation and application of a water-soluble heteropolysaccharide [一種水溶性雜多糖及其制備方法和用途]. Chinese Patent CN 1425693A (published on 25 June 2003)
  • The preparation and application of an antitumor water-soluble heteropolysaccharide [一種具有抗腫瘤活性的水溶性雜多糖及其製備方法和用途]. Chinese Patent CN 1425694A (published on 25 June 2003)
  • Extract of a medicinal mushroom, Polyporus rhinocerusCooke and composition of the same having antiproliferation of cancer cells and immune enhancing activity[具有抗癌與免疫增强活性的虎乳灵芝提取物及其制備方法]. Chinese Patent CN 200510114299.4 (published on 5 February 2010)
  • Extraction of Polyporus rhinocerus Cooke with antitumor and immune-enhancing activities and preparation thereof [具有抗癌與免疫增强活性的虎乳灵芝提取物及其制備方法]. Hong Kong SAR Patent HK1101770 (published on 21 January 2011)


Professional Activities

Editorial membership

  • Associate Editor of the Bioactive Carbohydrates and Dietary Fibre
  • Member of the Advisory Board of Journal of Agricultural and Food Chemistry
  • Member of the Editorial Board of International Journal of Medicinal Mushrooms
  • Member of the Editorial Board of Food Hydrocolloids for Health
  • Member of the Editorial Board of Food Science and Human Wellness
  • Member of the Editorial Board of Food Science (Shipin Kexue)

Professional membership

  • Member of the Institute of Food Technologists (IFT)
  • Member of the American Chemical Society (ACS)
  • Professional Member of the Australian Institute of Food Science and Technology (MAIFST)

Professional services

  • Served as Vice-chairman of the International Food Safety Association (since 2011)
  • Served as the Expert Panel member (Food Science and Nutrition) of the Hong Kong Food Science and Technology Association (since 2011)
  • Served as the Advisor of the Hong Kong Nutrition Association (since 2010)
  • Served as the Advisor of the Hong Kong Public Health Inspector Association (since 2009)
  • Served as the Chairman of the Hong Kong Food Science and Technology Association (2004-2005).
  • Served as the Vice-chairman of the Hong Kong Food Science and Technology Association (1997-2003).


Others

Community and Educational Services

  • External Examiner of Department of Food and Health Sciences (DFHS), Technological and Higher Education Institute of Hong Kong (THEi) (2024)
  • Member of the Self-evaluation Review Panel for the Programme Area Accreditation (PAA) in the Area of Sports and Recreation Management in the Technological and Higher Education Institute of Hong Kong (THEi) (2024)
  • External reviewer of the HKU SPACE Po Leung Kuk Stanley Ho Community College for Higher Diploma in Nutrition and Food Management (2023)
  • Concentration Studies Academic Advisor (CSAA) for Associate Degree (AD) Programme in Nutrition and Food Management, Hong Kong Baptist University College of International Education (CIE) (2021-2025)
  • Member of the Assessment Panel on Technology Education Key Learning Area Chief Executive’s Award for Teaching Excellence (CEATE) Education Bureau, Government Secretariat, Hong Kong SAR. (2023)
  • External member of the Review Panel of Master of Science in the field of Food Safety and Toxicology at the University of Hong Kong (HKU) (2021)
  • Member of the Faculty Advisory Committee (Management and Hospitality) of the Technological and Higher Education Institute of Hong Kong (THEi) (2016-2020)
  • Appointed as Specialist of the Hong Kong Council for Accreditation of Academic and Vocational Qualifications (HKCAAVQ) (Since 2016)
  • External Reviewer of School of Humanities and Social Science of The Chinese University of Hong Kong (Shenzhen) (Since 2019)
  • Chairperson of the Internal Validation Panel for the Bachelor of Science (Hons) in Food Science and Safety of the Technological and Higher Education Institute of Hong Kong (THEi) (2014 - 2019)
  • External Academic Adviser and Examination Paper Moderator of the HKBU College of International Education on Associate Degree of Food Safety and Environmental Health (2014 - 2019)
  • External Member of the Internal Validation Panel for BA (Hons) in Chinese Culinary Management with Design of the Technological and Higher Education Institute of Hong Kong (THEi) (2012 - 2015)
  • External Examiner of the Professional Diploma in Waste Management and Meat and Foods Inspection for Food and Environmental Hygiene Department of the Li Ka Shing Institute of Professional and Continuing Education (2008 - 2015)
  • External Examiner of the Hospitality Industry Training and Development Centre (HITDC) and Chinese Cuisine Training Institute (CCTI) of the Vocational Training Council (VTC) (2008 - 2015)
  • Member of the Curriculum Development Council (CDC) and Hong Kong Examinations and Assessment Authority (HKEAA) Committee on Technology and Living (senior Secondary), Education Bureau of the HKSAR Government (2008 - 2017)
  • Appointed as Moderator of the Technology and Living (Food Science and Technology) Papers 1 & 2 (E & C) (Practice Paper) of the Hong Kong Examinations and Assessment Authority (2010 - 2015)
  • Appointed as member of the Expert Committee on Food Safety, Food and Health Bureau, Government Secretariat of the HKSAR Government (2008 - 2010)